It's looks like the firewall passing a good amount of traffic, but still not able to identify the correct application-signature. Do you have a chance to take a packet capture. We can relay that PCAP through a LINUX REPLAY server and let you know if you need to contact with PAN support to open an App-ID BUG.
In the mean time, you may also try app-override once.
Did you ever get this one resolved? I have a newly configured PA-500 and noticed the same issue for our iSCSI traffic. It is a Dell EqualLogic. There is already a Application ID for iscsi for tcp/3260; however in our QoS reports it is shown as unknown-tcp
For traffic like iSCSI your best bet is to get this into a segregated vlan that does not transit routers and firewalls if at all possible.
If it must transit the PA, create an application override to improve performance and insure there is a little latency as possible on this traffic.
iSCSI traffic has been segregated into its own network (own switch); however, we do send bits over our firewall/routers for replication. The traffic is coming and going between our network here and our offsite location. As one could imagine, this data is appearing in all of the reports and typically on the top5 due to the about of bits being sent offsite (for DR).
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