A helpful blurb in the admin guide will answer most questions, see here. 1) No size limits, all 3 threat prevention profiles (antivirus, antispyware, vulnerability protection) scan the entire session. You are able to see which decoders are utilized in your antivirus settings. 2) See link. 3) All files are checked against wildfire, if there is a signature for the file then it will not be uploaded. If there isn't a signature (it's a new file), it will be uploaded.
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