@BruceBennett @MickBall Our mail is hosted by a company for the UK public health service. When on the LAN, we connect to the Exchange servers with a private IP range, via our public health ISP/WAN provider.. When off LAN, ie. in a public airport lounge, we can still connect to the same Exchange servers for our mail, via public IPs. Don't know the full set up of the Exchange servers, as this is managed externally, but that's what I've figured out. I expected MS Outlook just to work, once I was logged in via GlobalProtect, as effectively, I was on the corporate LAN. Mapping to shared drives etc all worked fine along with everything else. Just seemed bizarre MS Outlook didn't. How I eventually got MS Outlook to work via GlobalProtect, was I had to create a static route with the private IP range and point it back into my inside LAN facing interface (my Trust zone). All been fine since.
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