Hello Bart,
Your research is correct. We do not create signatures for specific hash values because it is both inefficient, and easily bypassed with a minimal change to the original file.
The performance impact is difficult to determine in a hypothetical situation due to the limitless environmental variables. The short answer though is yes, there will be an impact to utilizing large numbers of custom signatures. If you intend to block a large number of files using customer signatures, instead of using hashes, we suggest you identify a unique character string in the file and utilize if after thorough testing, as this improves your changes of catching multiple variants of the same malware.
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