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07-18-2025 10:16 AM
Hey everyone,
I am working on a project to integrate Cisco Catalyst 9500/Nexus 9300 switches with Palo Alto PA-5450 with PA-5400-NC-A cards using 100G QSFP transceivers. Specifically, I was testing with below transceivers.
Cisco QSFP-100G-SR4-S
Palo Alto T-Q28-100G-S4
Firewalls are running 11.1.4-h18.
Non-Working combination.
Working combination:
Test 3 and 4 of the working and non-working combination is essentially swapping the QSFPs between devices. It seems like the Palo Alto 5450 are having issues with T-Q28-100G-S4 but they work with Cisco QSFPs.
Have others seen similar behavior? Are there any known compatibility notes or optical tuning nuances between these platforms that I might’ve missed? Our team has opened a case with Palo Alto TAC as well.
Thanks in advance!
Thanks
Asad
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