My appologies, I didn't look at the threat-id very close and mistook it for a error that we were having earlier.
1) Make sure that your Vulnerability Protection Profile isn't changed from the default action.
2) In the meantime you might want to setup a rule that allows the application connection from Trust users to that specific IP address with everything except a Vulnerability Protection Profile to mediate the issue for the time being. If I would have to guess though your Protection Profile is set to something other then default.
It might be a good idea to have your programmers look at the application though. It sounds like if someone enters in the wrong password then the application is rapidly trying to login without a pre-defined wait period between authentification tries. Unless this is happening everytime a user logs in but I imagine it would be a more pressing issue if they physically could not access the application.
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