Here is a document that explains a reasoning and resolution for your issue:
Basically, we need to make sure that we have a file blocking profile set to Continue or Continue Forward and then make sure that it is applied to a security policy.
Hope that helps!
Make sure that your traffic for wildfire is not getting blocked. This can happen if you management traffic is passing through the firewall.
Here are the commands to verify wildfire
test wildfire registration
show wildfire status
Also under Device -->setup --> wildfire verify the following information is populated
If the configuration is populated you can try to put the server address manually.
The following doc shows the address as va-s1.wildfire.paloaltonetworks.com
Hope this helps you resolve the issue.
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