Hi @Ramees ,
PAN-OS 10.1 is so new that there is no recommended release for it yet -> https://live.paloaltonetworks.com/t5/customer-resources/support-pan-os-software-release-guidance/ta-.... I have it installed on 1 production firewall with no issues. I see no known issues related to the PA-850 -> https://docs.paloaltonetworks.com/pan-os/10-1/pan-os-release-notes.html.
PAN-OS 10.1.3 would have the most bug fixes. So, I would go with it. If you want new features in 10.1, I would go with the latest release. Otherwise, 10.0 is definitely more safe. Typically, I wait 12 months before putting a new release into production.